Neysan Rafat What Do We Know About the Potential of Endothelial Cells in Treating Acute Lung Injury?
Neysan Rafat is a doctor at the University Clinic Heidelberg, Germany. He specializes in Pediatrics, Nephrology, and Emergency Medicine. In 2009, Rafat won the Young Investigator Award of the Medical Faculty Heidelberg, followed by the Fokko van der Woude Research Grant of the German Kidney Foundation in 2010. In his current research, Rafat focuses on the course of a Sepsis, reviewing the research done and exploring further research that could help move the knowledge on Sepsis.
Area of Research
Endothelial Dysfunction and Regeneration, Vascular Stem Cell Biology, Vascular Stem Cell Therapy
since 2015
Specialist for Pediatrics
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
General Pediatrics, Pediatric Neurology, Metabolism, Gastroenterology, Nephrology
since 2010
Junior Group Leader
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
General Pediatrics, Pediatric Neurology, Metabolism, Gastroenterology, Nephrology
2009-2011
Postdoctoral Fellow
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
Department of Internal Medicine I and Clinical Chemistry
2009-2015
Resident
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
General Pediatrics, Pediatric Neurology, Metabolism, Gastroenterology, Nephrology
2007-2009
PhD-Student
University of Groningen
Department of Pathology and Medical Biology
2004-2007
Doctoral Student
University of Mannheim (Universität Mannheim)
Department of Anaesthesiology and Critical Care Medicine
2009
PhD in Medical Biology
University of Groningen
2007
MD (Dr. med.)
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
2007
State Exame in Medicine
Heidelberg University (Ruprecht-Karls-Universität Heidelberg)
- German Society of Pediatrics and Adolescent Medicine
- German Society of Pediatric Nephrology
- German Society of Nephrology
Fellowships
- Young Investigator Award of the Medical Faculty Heidelberg (2009)
Prizes
- Roger-Bone-Award 2008 of the German Sepsis Society (2008)
- Poster award of the German Sepsis Society at the „3rd International Congress Sepsis and Multiorgan Dysfunction" in Weimar (2007)
- Winner of the Session “Immunology” at the “15th European Student Conference” in Berlin/Germany (2004)
- Medical Student Jury Award at the „11th International Student Congress of Medical Sciences“ in Groningen/Netherlands (2004)
- Fokko van der Woude- Research Grant 2010 of the German Kidney Foundation and the German Society of Nephrology
A positive outcome of an acute lung injury, a by-product of sepsis, is closely linked to a repair process in which endothelial progenitor cells are involved. These cells derive from the bone marrow and circulate in the blood stream. In the past ten years a lot was published on endothelial regeneration. The paper presented in this video aims at bringing together this research to create an overview of what has been achieved already, how the findings contrast and amend each other and what is still unknown and worth tackling. NEYSAN RAFAT explains that the different studies such as animal studies, clinical studies and in-vitro studies can be compared even though there are two methods used which often come to contrasting results. Based on this gathered knowledge future ways of therapy using endothelial regeneration can be examined.
LT Video Publication DOI: https://doi.org/10.21036/LTPUB10066
Endothelial Progenitor Cells in Regeneration after Acute Lung Injury: Do They Play a Role?
- Neysan Rafat, Burkhard Tönshoff, Angelika Bierhaus and Grietje C. Beck
- American Journal of Respiratory Cell and Molecular Biology
- Published in 2013